High-throughput screening of functional antigen and TCR via Jurkat reporter combine with droplet microfluidics
Source: CNGBdb Project (ID CNP0003756)
CC BY 4

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Description: Here, we developed an integrated platform which combine with Jurkat reporter system, DNA barcoding and droplet microfluidics to enable the library-on-library functional antigens and TCR screening. Next, analysis of T cell activation related genes and DNA barcode based on single-cell RNA-sequencing can determine the specific recognition between the antigens and their functional TCRs.
Data type: Raw sequence reads
Sample scope: Monoisolate
Submitter: 付云芸(fuyunyun); 杭州华大生命科学研究院
Release date: 2023-12-30
Last updated: 2023-12-30
Statistics: 6 samples; 12 experiments; 12 runs
Data size: 262.94GB