Project name: antler

Description: Deer antler is the only mammalian appendage in nature that can fully regenerate periodically every year. This organ is composed of cartilage, bone, blood vessels, nerves and skin, and its growth rate ranks high among mammals, with the fastest growth rate of 2.7 cm/day, and no canceration. Regarding the differentiation and regeneration of deer antler stem cells, at the molecular level, individual important functional genes and signaling molecules have been studied, such as TGFB1, UHRF1, CCND1, TB10, SHH, NOTCH1, S100A4, WNT4 and S100A10, etc. The research progress of deer antler biology at the molecular level, but it cannot systematically and clearly reveal the fine spatiotemporal map of gene expression regulated and differentiated by deer antler stem cells at the overall level. In addition, transcriptomic and proteomic analysis of antler tissue, which measures the average value of gene expression in a group of cells, makes it difficult to identify the heterogeneity of gene expression regulation between different differentiated cell types. Single-cell omics technology can make up for the above deficiencies, and there is no relevant report on the application of single-cell technology to deer antler research.

Data type: Raw sequence reads; Transcriptome or Gene expression

Sample scope: Environment

Relevance: Model organism

Release date: 2025-11-09

Last updated: 2025-11-09

Data size: 1.25TB