Characterization of a small plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain of Streptococcus sanguis isolated from dental plaque.
Antimicrob Agents Chemother, 1978/5;13(5):884-7.
Yagi Y, McLellan TS, Frez WA, Clewell DB
PMID: 96738
Impact factor: 5.938
Abstract
A plasmid determining resistance to erythromycin (inducible), lincomycin, and vernamycin B(alpha) was isolated from a strain of Streptococcus sanguis isolated from dental plaque of a patient who had been on erythromycin therapy for an extended period of time. The plasmid, designated pAM77, had a molecular weight of 4.5 x 10(6) and was present to the extent of one to two copies per bacterial chromosome. The plasmid could transform S. sanguis strain Challis.
MeSH terms
Anti-Bacterial Agents; DNA, Bacterial; Dental Plaque; Erythromycin; Humans; Lincomycin; R Factors; Streptococcus sanguis; Virginiamycin
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