Activation of fungal alpha-amylase by dithioerythritol.

Acta Biol Med Ger, 1979;38(11-12):1539-42.

Ulbrich R, Schellenberger A

PMID: 95240

Abstract
The activity of fungal alpha-amylase has been shown to be influenced by disulfide-reducing reagents. Thus, the enzymatic activity increases in the presence of dithioerythritol or 2-mercaptoethanol. L-Cysteine is also capable of increasing the activity, but the activation competes with an inactivation reaction which dominates at higher reagent concentrations (greater than 20 mM). A possible scheme interpreting the results is given.
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