[Stimulating determinants of the secondary mixed lymphocyte reaction (MLR-II)].
C R Seances Acad Sci D, 1979/9/24;289(5):477-80.
PMID: 93033
Abstract
An anti-Ia immune serum (A . TL anti-A . TH) directed to the antigens of the stimulating cell, blocked the MLR-II. A significant correlation was observed between the anti-Ia reactivity of the immune serum, studied against a panel of eleven original H-2 haplotypes and the reactivity against the same panel of the in vitro primed responding cells (A . TL anti-A . TH). These results confirm the hypothesis that Ia antigens are the structures stimulating the MLR-II.
MeSH terms
Animals; Antibody Formation; Antigen-Antibody Complex; Cells, Cultured; Epitopes; Immune Sera; Mice; T-Lymphocytes
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