Radiation-released histamine in the rhesus monkey as modified by mast-cell depletion and antihistamine.
Experientia, 1977/8/15;33(8):1047-9.
PMID: 70375
Abstract
4000 rads of mixed gamma neutron radiation administered to rhesus monkeys released a significant amount of histamine into their circulation. When the monkeys were treated with a mast-cell histamine depleter (compound 48/80) for 4 days and then irradiated, no increase in circulating histamine was seen. When 48/80 was give 20 min after irradiation, only a slight increase in histamine was seen, indicating that 4000 rads had released most of the mast-cell histamine.
MeSH terms
Animals; Chlorpheniramine; Female; Haplorhini; Histamine H1 Antagonists; Histamine Release; Macaca mulatta; Male; p-Methoxy-N-methylphenethylamine
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