Distribution of a bombesin-like peptide in human gastrointestinal tract.
Lancet, 1976/5/22;1(7969):1109-10.
Polak JM, Bloom SR, Hobbs S, Solcia E, Pearse AG
PMID: 57512
Impact factor: 202.731
Abstract
The bombesin group of hormonal peptides produced in the amphibian skin have powerful actions on the mammalian gastrointestinal tract. In man a bombesin-like material was found in an endocrine cell which is widely distributed in the gastrointestinal mucosa. This has tentatively been identified as belonging to the non-enterochromaffin cell groups. The large number of cells containing a bombesin-like peptide suggests that this substance may be important in human physiology.
MeSH terms
Brunner Glands; Colon; Duodenum; Fluorescent Antibody Technique; Gastric Mucosa; Gastrointestinal Hormones; Histocytochemistry; Humans; Ileum; Intestinal Mucosa; Jejunum; Peptides; Staining and Labeling
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