Cross reactivity between H-2K and H-2D products. II. Identification of the cross reacting specificities.
Transplantation, 1975/12;20(6):443-56.
PMID: 54965
Impact factor: 5.385
Abstract
Absorption analyses were conducted on antisera which had previously been shown to detect cross reactivity between the H-2K and H-2D gene products. These analyses revealed that the cross reactions were due to known public H-2 specificities. Identification of cross reactive anti-H-2.3 and anti H-2.5 antibodies confirmed earlier predictions that genes controlling these specificities should be localized at opposite ends of the H-2 complex. The finding of H-2.29 activity on both sides of the S region clarified ambiguities encountered in assigning this specificity to certain recombinant types. Results with H-2.36 support the suggestion that this determinant may also be specified by both H-2K and H-2D genes.
MeSH terms
Absorption; Animals; Antibody Specificity; Cross Reactions; Epitopes; Histocompatibility Antigens; Mice; Mice, Inbred Strains; Protein Biosynthesis
More resources
EndNote: Download