[Effect of hypothalamic implants changing monoamine levels on continuous estrus in rats induced by androgen treatment in the neonatal period].
C R Seances Soc Biol Fil, 1975;169(1):113-7.
Tournigant JC, Arnaud O, Passouant-Fontaine T
PMID: 52387
Abstract
The constant estrus induced by neonatal androgenization in the female rat may be disrupted following a drug-induced change of the monoamine levels in the preoptic area and arcuate nucleus of the median eminence. The most precise effect is obtained with 5-HT. This is in favour of a predominant alteration of the serotonergic system which seems to be involved in the sexual differentiation of the brain.
MeSH terms
Adrenergic Agents; Animals; Animals, Newborn; Dopamine; Drug Implants; Estrus; Female; Fenclonine; Hydroxydopamines; Hypothalamus; Neurotransmitter Agents; Norepinephrine; Pregnancy; Preoptic Area; Rats; Reserpine; Serotonin; Testosterone
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