Rat tumour allografts evoke anaphylactic antibody responses.
Immunology, 1975/6;28(6):1033-40.
PMID: 48504
Impact factor: 7.215
Abstract
In vitro assays of release of histamine from peritoneal mast cells showed that Wistar rats produced anaphylactic antibody in response to a single immunization with an allogeneic sarcoma. The response occurs early after immunization, and no adjuvant is needed. The thermolability of the anaphylactic antibody suggests that it is IgE.
MeSH terms
Adjuvants, Immunologic; Anaphylaxis; Animals; Antibodies, Neoplasm; Antibody Formation; Ascitic Fluid; Bordetella pertussis; Fibrosarcoma; Histamine; Histamine Release; Hot Temperature; Immunization; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Neoplasm Transplantation; Rats; Sarcoma, Experimental; Transplantation, Homologous
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