Leucapheresis in severe rheumatoid arthritis.

Ann Rheum Dis, 1979/2;38(1):40-4.

Tenenbaum J, Urowitz MB, Keystone EC, Dwosh IL, Curtis JE

PMID: 434945

Impact factor: 27.973

Abstract
Two patients with severe seropositive rheumatoid arthritis previously unresponsive to conventional therapy have been treated with leucapheresis. This technique involves continuous cell separation daily to remove primarily lymphocytes. Clinical improvement was recorded with the use of standard rheumatological measures of inflammation. It is concluded that leucapheresis may help in the management of severely active rheumatoid arthritis when conventional therapy has been unsuccessful.
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