A quantitative evaluation of rheumatoid arthritic activity with Tc-99m HEDP.
J Nucl Med, 1977/10;18(10):973-6.
Park HM, Terman SA, Ridolfo AS, Wellman HN
PMID: 409749
Impact factor: 11.082
Abstract
In an attempt to develop a quantitative method of evaluating rheumatoid arthritic activity, Tc-99m HEDP joint uptake values and joint-to-bone ratios were studied in ten adult rheumatoid arthritic patients and 17 nonarthritic patients. A joint-to-bone activity ratio of 1.8 at the fourth hour after injection (RA Index) discriminated clinically active rheumatoid arthritic joints from control joints with 95% accuracy. Serial studies on five patients during drug trial demonstrated a positive correlation between RA Index and the clinical manifestations of rheumatoid arthritic activity. The RA Index may be a useful quantitative parameter for evaluation of rheumatoid arthritic activity following therapy.
MeSH terms
Adult; Arthritis, Rheumatoid; Etidronic Acid; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Radionuclide Imaging; Technetium; Technology, Radiologic
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