A comparative assessment of carbuterol, fenoterol and hexoprenaline in allergic asthma.
S Afr Med J, 1978/6/17;53(25):1011-5.
van As A, McDonald I, Gebhardt T, Dowdeswell R
PMID: 358427
Impact factor: 2.162
Abstract
Carbuterol tablets (2,0 mg) were compared with the tablets of fenoterol (2,5 mg) and hexoprenaline (1 mg). The three drugs were shown to be equally effective for a period of 4 hours, but carbuterol and fenoterol exerted a statistically significant bronchodilating action for 7 and 8 hours respectively, while the action of hexoprenaline lasted for 4 hours in the majority of patients. The aerosols of carbuterol (200 mg) and fenoterol (400 mg) appeared to be similar in inhibiting exercise-induced asthma, whereas hexoprenaline (200 mg) did not appear to be as effective.
MeSH terms
Adolescent; Adult; Aerosols; Asthma; Blood Pressure; Bronchi; Clinical Trials as Topic; Ethanolamines; Female; Fenoterol; Heart Rate; Hexoprenaline; Humans; Male; Middle Aged; Phenethylamines; Pulmonary Ventilation; Tablets
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