Rena transplantation and HLA-A, B matching. Theoretical considerations concerning pool size.
Scand J Urol Nephrol Suppl, 1977;(42):203-6.
PMID: 356211
Abstract
The rate of improvement in HLA-matching quality with increasing pool size is predicted. The frequency of HLA-A, B compatible matches increases rapidly up to approximately 47% for pool size 1000 and from then on the increase is more moderate while for HLA-A, B fullhouse-identical matches the increase in frequency is slower and more constant, the expected frequency being approximately 33% at a pool size of 2500. The import/export balance between two cooperating pools is estimated for various relative pool sizes and transplantation activities.
MeSH terms
Gene Frequency; HLA Antigens; Histocompatibility Testing; Humans; Kidney Transplantation; Models, Biological; Statistics as Topic; Transplantation, Homologous
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