A study of the effectiveness of propranolol in menopausal hot flushes.
Br J Obstet Gynaecol, 1978/6;85(6):472-5.
Coope J, Williams S, Patterson JS
PMID: 350262
Abstract
A prospective, double-blind, randomized comparison of propranolol, 40 mg three times daily, and matching placebo showed propranolol to be no more effective than placebo in controlling hot flushes in a group of 25 perimenopausal women. Other menopausal symptoms, such as insomnia and palpitations, were equally unaffected. However, a very close correlation was found between the daily atmospheric temperature and the number of flushes occurring in the group.
MeSH terms
Adult; Aged; Climacteric; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Middle Aged; Propranolol; Temperature
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