Acute poststreptococcal glomerulonephritis in Maracaibo. II: Studies on the incidence, nature, and significance of circulating anti-immunoglobulins.
Ann Rheum Dis, 1979/6;38(3):257-61.
McIntosh RM, Rabideau D, Allen JE, Garcia R, Rubio L, Carr RI, Rodriguez-Iturbe B
PMID: 314784
Impact factor: 27.973
Abstract
Antiglobulins were measured in the sera of 82 patients with acute poststreptococcal glomerulonephritis and correlated with C1q binding activity, serum levels of immunoglobulins and C3, site of infection, antibody titres to streptococcal enzymes, and the duration of the nephritis and interval from infection. Raised serum antiglobulins were found in 89.2% of the patients. In addition, raised titres were detected at any time during the course of the disease and very early after streptococcal infection. The finding of antiglobulins soon after the infection suggests the possibility that they appear as a primary event in the disease.
MeSH terms
Acute Disease; Adolescent; Adult; Antibodies, Anti-Idiotypic; Child; Child, Preschool; Glomerulonephritis; Humans; Immunoglobulins; Rheumatoid Factor; Streptococcal Infections; Time Factors
More resources
Full text:
Europe PubMed Central; PubMed Central
EndNote: Download