3'-deoxyadenosine and implantation of delayed blastocysts in mice.
J Endocrinol, 1979/6;81(3):351-4.
PMID: 313973
Impact factor: 4.669
Abstract
Pregnant mice were ovariectomized 3 days after mating and pregnancy was maintained by progesterone treatment. Different regimens of intraperitoneal injections of 3'-deoxyadenosine were applied 3 days after ovariectomy. Repetition of the injections at 3 h intervals induced a significant rate of implantation by delayed blastocysts. Other types of treatment with 3-deoxyadenosine as well as adenosine injections were found to be ineffective. Paradoxically, 3'-deoxyadenosine treatment had an adverse effect on the overall pregnancy rate found at autopsy.
MeSH terms
Animals; Blastocyst; Castration; Deoxyadenosines; Embryo Implantation; Embryo Implantation, Delayed; Estradiol; Female; Injections, Intraperitoneal; Mice; Pregnancy; Progesterone
More resources
EndNote: Download