[Indicators of cellular and humoral immunity in chronic opisthorchiasis].
Zh Mikrobiol Epidemiol Immunobiol, 1978/2;(2):78-80.
Belozerov ES, Filippov EG, Sadykov KB, Arkhipov GS, Strel'nikova LP
PMID: 307318
Abstract
Quantitative content of T- and B-lymphocytes in the peripheral blood was studied after Mendes in 30 patients suffering from chronic opisthorcosis and in 30 practically healthy persons; immunoglobulins--M, G, and A were examined after Mancini, and the presence of autoantibodies in the blood serum was studied by indirect method of mast cells degranulation. There was revealed a reduction of the T-cell count to 28.8 +/- 2.28% (normal value--52.9 +/- 3.32%) and a fall of IgM level to 163.4 +/- 16.2 (207.2 +/- 10.5 in donors) in the patients; macrophages count was almost doubled. Autoantibodies to the antigens of the liver, gastric mucosa and the gall bladder wall were revealed in 1/3 of the patients.
MeSH terms
Autoantibodies; B-Lymphocytes; Cell Count; Humans; Immunity, Cellular; Immunoglobulins; Lymphopenia; Opisthorchiasis; Phagocytosis; T-Lymphocytes
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