Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol.
Science, 1975/12/05;190(4218):991-2.
McLachlan JA, Newbold RR, Bullock B
PMID: 242076
Impact factor: 63.714
Abstract
Sixty percent of the male offspring from pregnant mice treated with diethylstilbestrol during gestation were sterile. The affected animals had gonadal changes which included intra-abdominal or fibrotic testes, or both. Additionally, nodular masses in the ampullary region of the reproductive tract were observed in 6 of 24 animals; one of these appeared to be preneoplastic.
MeSH terms
Abnormalities, Drug-Induced; Animals; Cryptorchidism; Diethylstilbestrol; Epididymis; Female; Infertility, Male; Male; Maternal-Fetal Exchange; Mice; Pregnancy; Testis
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