Simultaneous pharmacokinetics of alclofenace in plasma and synovial fluid in patients with rheumatoid arthritis.
Curr Med Res Opin, 1975;3(5):264-7.
Thomas GM, Rees P, Dippy JE, Maddock J
PMID: 241595
Impact factor: 2.705
Abstract
The simultaneous pharmacokinetics of alclofenac in the plasma and synovial fluid of 10 patients with rheumatoid arthritis were studied after a single 1 g. oral dose. A gas-liquid chromatographic method was used for assaying alclofenac in both plasma and synovial fluid. Alclofenac readily appears in the plasma and synovial fluid.
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