Influence of albumin on rubella virus hemagglutination and the hemagglutination-inhibition test.

Can J Microbiol, 1975/8;21(8):1172-7.

Campbell JB, Grunberger T, Ellins ML

PMID: 240497

Impact factor: 3.226

Abstract
The HEPES-saline-albumin-gelatin (HSAG) diluent found optimal for agglutination of fowl erythrocytes by rubella virus antigen is also optimal for agglutination of trypsin-treated human group O cells. Albumins from different commercial sources, however, can have varying inhibitory effects on rubella hemagglutination titers. This can have a significant effect on the hemagglutination-inhibition test since antibody titers measured by this procedure are related to the amount of antigen used.
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