[Correlation of splenomegaly and blood picture changes in graft vs host reaction of the mouse].
Blut, 1975/10;31(4):229-38.
PMID: 240470
Abstract
The early phase of graft-versus-host-reaction is characterized by a rapid decline of lymphocytes in the peripheral blood, with a minimum between days 9 and 11, and return to normal until day 20 after spleen cell grafting. Erythrocytes and hematocrit do not change during this period. There is no causal correlation between splenomegaly and lymphopenia. Lymphopenia provides a criterium for experimental graft-versusu-host-reaction equivalent to the spleen-index.
MeSH terms
Animals; Erythrocyte Count; Graft vs Host Reaction; Hematocrit; Leukocyte Count; Lymphocytes; Lymphopenia; Mice; Mice, Inbred Strains; Splenomegaly; Time Factors
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