Sepsis, resuscitated hemorrhagic shock and "shock lung:" An experimental correlation.
Ann Surg, 1975/9;182(3):218-27.
PMID: 240329
Impact factor: 13.787
Abstract
Dogs were submitted to hermorrhagic shock, resuscitated shock and resuscitated shock plus a pulmonary bacterial insult. Pulmonary familure was absent in dogs submitted only to shock or to shock and its resuscitation. The addition of usually sub-lethal amounts of micro-organisms to the shock-resuscitated lung caused rapid death from pulmonary failure. Pulmonary failure was demonstrated by increased lung weight, hypoxemia, decreased compliance and a hemorrhagic destruction of lung tissue. These findings strongly support recent concepts of an infective genesis of "shock lung" in man.
MeSH terms
Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Hydrogen-Ion Concentration; Hypoxia; Lung; Lung Compliance; Pseudomonas Infections; Pulmonary Edema; Respiratory Insufficiency; Respiratory Tract Infections; Resuscitation; Shock, Hemorrhagic; Tidal Volume; Vascular Resistance; Ventilation-Perfusion Ratio
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