Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.
Experientia, 1975/8/15;31(8):964-5.
Schachter M, Karpinski E, Haines V
PMID: 239857
Abstract
The histamine H2-receptor antagonist, metiamide, inhibits the acid gastric secretion produced by chloralose-urethane anaesthesia in dogs carrying gastric cannulae chronically. This secretion is also prevented by atropine and hexamethonium. "Spontaneous" gastric secretion of vagal origin in conscious dogs is also blocked by metiamide.
MeSH terms
Animals; Atropine; Chloralose; Dogs; Gastric Juice; Gastric Mucosa; Hexamethonium Compounds; Histamine H1 Antagonists; Metiamide; Thiourea; Urethane; Vagus Nerve
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