Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography.
J Pharm Pharmacol, 1975/3;27(3):167-71.
Cole WJ, Mitchell RG, Salamonsen RF
PMID: 237998
Impact factor: 4.81
Abstract
A method for the quantitative determination of plasma concentrations of chloral hydrate by electron capture gas chromatography is described. Characterization by multiple ion monitoring confirms, for the first time, that chloral hydrate exists as a transient metabolite of trichloroethylene in man.
MeSH terms
Anesthesia; Chloral Hydrate; Chromatography, Gas; Humans; Mass Spectrometry; Time Factors; Trichloroethylene
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