Distribution of NAD(P)H-dependent cytochrome P-450 mixed function oxidase system in the brush border membrane of rabbit kidney cortex.
Biochim Biophys Acta, 1975/7/03;394(3):406-15.
PMID: 236788
Abstract
Optical and magnetic studies were made on subfractions of rabbit kidney cortex. Cytochrome P-450 and cytochrome b5-dependent mixed function oxidase systems were localized mainly in the brush border membranes and microsomes. Cytochrome P-450-dependent mixed function oxidases in the membranes comprised both an NADPH-dependent system and an NADH-dependent system.
MeSH terms
Animals; Cell Fractionation; Cell Membrane; Cytochrome P-450 Enzyme System; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport; Kidney Cortex; Kinetics; Male; Microscopy, Electron; Microsomes; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Oxidoreductases; Proteins; Rabbits; Spectrum Analysis
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