Additional data on hepatic function tests in cystic fibrosis.
Acta Paediatr Scand, 1975/3;64(2):337-44.
Feigelson J, Pecau Y, Cathelineau L, Navarro J
PMID: 236631
Abstract
Fifty cystic fibrosis (CF) patients, of whom 9 had multilobular cirrhosis, were observed regularly for a period of 3 years and various liver function tests, indicating cytolysis, cholestasis and cellular insufficiency were performed. Immunoglobulin and prothrombin were assayed. In 9 patients with cirrhosis, the tests were generally abnormal. Two distinct biochemical patterns of cirrhosis were distinguished, one clearly cholestatic and the other of a more cellular type. The distinction was made on the basis of the IgA : Transferrin ratio and of gamma-glutamyl-transpeptidase levels. In the non-cirrhotic patients, a temporary increase of cytolysis and cholestasis was observed in 50% of the cases.
MeSH terms
Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Child; Child, Preschool; Cholinesterases; Cystic Fibrosis; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Infant; Leucyl Aminopeptidase; Liver; Liver Cirrhosis; Liver Function Tests; Male; Ornithine Carbamoyltransferase; Prothrombin; Serum Albumin; Transferrin; Vitamin B 12; gamma-Glutamyltransferase
More resources
EndNote: Download