Evidence for beneficial effect of intravenous glucose on the hemodynamic response to acute asphyxia.

Proc Soc Exp Biol Med, 1975/3;148(3):743-7.

Scholle SF, Griggs DM Jr

PMID: 236574

Abstract
Anesthetized rabbits were subjected to two 4-min periods of asphyxia with a 15-min recovery period intervening. During the recovery period animals received an iv infusion of either isotonic glucose or mannitol. Results indicated that glucose had a beneficial effect on systolic blood pressure during the second period of asphyxia. A direct metabolic action of glucose on the myocardium is favored as the explanation, but other possibilities include peripheral or neurohumoral effects.
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