Current therapy of hypertension. A pharmacologic approach.
Am J Med, 1975/4;58(4):489-94.
PMID: 235841
Impact factor: 5.928
Abstract
Adequate treatment of hypertension requires that the physician understand the pharmacologic actions of antihypertensive agents. Although no drug is without adverse reactions, it should be possible to choose an agent or combination of agents which can effectively lower blood pressure and be tolerated by the patient. The indications, proposed mechanisms of actions and adverse effects of the following antihypertensive drugs are discussed: thiazide diuretics, spironolactone, triamterene, trimethaphan, Rauwolfia alkaloids. guanethidine, bethanidine, methyldopa, clonidine, pargyline, propranolol, hydrazaline, minoxidil, guancydine, diazoxide and sodium nitroprusside.
MeSH terms
Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; Humans; Hypertension; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Reserpine; Secologanin Tryptamine Alkaloids; Sodium Chloride Symporter Inhibitors; Spironolactone; Sympathetic Nervous System; Synaptic Transmission; Triamterene; Vasodilator Agents
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