Abnormal intrafusal muscle fibres in myotonic dystrophy: a study using serial sections.
J Neurol Neurosurg Psychiatry, 1975/1;38(1):91-9.
PMID: 235011
Impact factor: 13.654
Abstract
Studies of the extent and complexity of intrafusal muscle fibre splitting in myotonic dystrophy have been carried out in three spindles obtained at muscle biopsy, and in nine spindles found in the lumbrical muscle of a case that came to necropsy. It is suggested that splitting, due to mechanical stresses, leads to a regenerative response in the separated fragments.
MeSH terms
Adenosine Triphosphatases; Female; Histocytochemistry; Humans; Microscopy, Electron; Middle Aged; Mitochondria, Muscle; Muscle Spindles; Muscles; Myofibrils; Myotonic Dystrophy; NADH, NADPH Oxidoreductases; Regeneration; Sarcoplasmic Reticulum; Syndrome
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