[Cellular immunity in actively conditioned recipients of renal allotransplants (author's transl)].
Dtsch Med Wochenschr, 1975/2/21;100(8):370-2.
Haefen UV, Garovoy MR, Wren SF, Martins AC, Wilson RE
PMID: 234839
Impact factor: 0.653
Abstract
The presence of circulating "killer" cells was demonstrated in actively "conditioned" rats with permanently accepted renal allotransplants. Immunocompetant cells of these animals were able to develop a normal graft-versus-host reaction 100 and 200 days after the transplantation. The ability of these recipients simultaneously to accept secondary donor-specific skin transplants without demonstrable immunological rejection is compatible with the concept that the cytotoxic potential of these cells in vivo is inhibited by enhancing antibodies.
MeSH terms
Animals; Antibodies; Graft vs Host Reaction; Histocompatibility Antigens; Immunity, Cellular; Kidney Transplantation; Male; Rats; Skin Transplantation; Time Factors; Transplantation Immunology; Transplantation, Homologous
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