[Fibre interaction with red blood cells or alveolar macrophages "in vitro" (author's transl)].
Rev Fr Mal Respir, 1979/12;7(7):717-22.
Jaurand MC, Bignon J, Magne L, Renier A, Lafuma J
PMID: 233435
Abstract
Haemolytic activities and effects on alveolar macrophages (AM) of various fibres were studied. UICC asbestos fibres and attapulgites either untreated or acid-leached were used. Amphiboles and commercial attapulgites were both cytotoxic on AM, but attapulgites and chrysotile were only haemolytic. Chrysotile fibres induced a release of B galactosidase; when acid treated these fibres were cytotoxic and less haemolytic. Acid treated amphiboles were more haemolytic than untreated.
MeSH terms
Asbestos; Asbestos, Amphibole; Erythrocytes; Hemolysis; In Vitro Techniques; Macrophages; Magnesium; Magnesium Compounds; Pulmonary Alveoli; Silicon; Silicon Compounds; Silicon Dioxide; beta-Galactosidase
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