Effect of prostaglandins on the increased corticosterone output induced by caffeine in the rat.
Prostaglandins Med, 1979/8;3(2):97-103.
De Pasquale A, Costa G, Trovato A, Ceserani R
PMID: 233218
Abstract
The effect of prostaglandins on the increase of corticosterone output induced by caffeine was investigated in rats. PGE2 and some synthetic prostaglandins (11-deoxy-derivatives), which stimulate steroid output in vitro, enhanced the effect of caffeine. Pretreatment with indomethacin inhibited the effect of caffeine.
MeSH terms
Adrenal Glands; Animals; Caffeine; Corticosterone; Cyclic AMP; Indomethacin; Male; Prostaglandins E, Synthetic; Rats
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