Appearance of immunoglobulin G Fc receptor in cultured human cells infected with varicella-zoster virus.
Infect Immun, 1979/11;26(2):770-4.
PMID: 232695
Impact factor: 3.609
Abstract
After infection with varicella-zoster virus, HeLa and human embryo lung cells developed a receptor for the Fc portion of human and rabbit immunoglobulin G. The receptor was detected by both hemadsorption and immunofluorescence, using antibody-coated erythrocytes and heat-aggregated immunoglobulin G. However, sheep erythrocytes sensitized with F(ab')2 of anti-sheep erythrocyte antibody did not adsorb to the receptor. When cell-free varicella-zoster virus was inoculated into the HeLa cell monolayer, the Fc receptor appeared at first 6 h after infection; varicella-zoster virus antigen in the cytoplasm and detectable cytopathic effects appeared later.
MeSH terms
Animals; Cell Line; Embryo, Mammalian; Erythrocytes; Fluorescent Antibody Technique; HeLa Cells; Hemadsorption; Herpesvirus 3, Human; Humans; Lung; Receptors, Fc; Sheep; Virus Replication
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