[Resistance of the Aujeszky's disease virus to gamma ray irradiation].
Vet Med Nauki, 1979;16(6):52-7.
Iordanov I, Kunev Zh, Khristova M
PMID: 232589
Abstract
Investigations on the resistance of Aujeszky's disease virus to gamma irradiation from a 60Co source were performed. The resistance of the virus was tested in vitro in a fluid medium of 50% Henk's balanced saline solution, 50% Eagle's medium MEM and a supplement of 10% normal calf serum as well as its resistance on artificially virus infected pig skin and greasy wool of sheep. It is established that virus inactivation in the fluid medium occurs following 1.6 Mrad gamma irradiation. The irradiated with lower than 1.6 Mrad gamma doses live virus particles form smaller than and with irregular oval shape and dentated plates as compared to the non-irradiated control virus. 1.5 Mrad gamma rays are needed to inactivate the virus on pig skin and greasy wheep's wool. The presence of lanoline in greasy sheep's wool, due to the alkaline pH (9--13) it produces, has an effect on the vitality of the virus both in the control and in the experimental samples.
MeSH terms
Animals; Dose-Response Relationship, Radiation; Gamma Rays; Herpesvirus 1, Suid; In Vitro Techniques; Radiation Tolerance; Sheep; Skin; Swine; Virus Cultivation; Wool
More resources
EndNote: Download