Phosphorus 31 NMR of neuroblastoma clonal lines. Effect of cell confluency state and dibutyryl cyclic AMP.
Neurochem Res, 1979/12;4(6):795-802.
Pettegrew JW, Glonek T, Baskin F, Rosenberg RN
PMID: 232546
Impact factor: 4.414
Abstract
Phosphorus nuclear magnetic resonance is used to study changes in the levels of the major phosphate-containing intermediary metabolites concomitant with induced cellular differentiation in the N-18 and C-46 neuroblastoma clonal lines. The study reveals differences between the 31P-NMR profiles of the two clonal lines and also striking differences attendant to dibutyryl cAMP-mediated morphological differentiation in the N-18 clone. Phosphorus-31 NMR would appear to provide a new technique with which to study genetic differentiation.
MeSH terms
Animals; Bucladesine; Cell Differentiation; Cell Division; Clone Cells; Magnetic Resonance Spectroscopy; Mice; Neuroblastoma; Organophosphorus Compounds; Phosphates; Phosphorus
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