Protective effect of polymyxin B sulfate in experimental enterobacterial infection in mice.
Can J Microbiol, 1979/9;25(9):995-8.
PMID: 232006
Impact factor: 3.226
Abstract
The mouse model of intraperitoneal enterobacterial sepsis was used to evaluate the anti-endotoxic effect of polymyxin B sulfate. Single or multiple therapeutic doses of polymyxin, administered either before or after lethal challenge with Serratia marcescens, produced statistically and clinically significant protective effects.
MeSH terms
Animals; Disease Models, Animal; Endotoxins; Enterobacteriaceae Infections; Limulus Test; Mice; Organ Specificity; Polymyxin B; Polymyxins
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