The effects of ultraviolet and ionizing radiation on herpesviruses, SV40 and adenoviruses in relation to the small-plaque effect.
Arch Virol, 1979;62(1):31-40.
Cameron KR, Tomkins LM, Eglin RP, Ross LJ, Wildy P, Russell WC
PMID: 231946
Impact factor: 2.685
Abstract
The small-plaque effect occurs with a wide range of herpesviruses following irradiation with ultraviolet light. The 37 per cent survival (D37) values, or dose required for one lethal hit (e-1), for herpes simplex, pseudorabies and pigeon herpesviruses in different cells indicate a broad spectrum of host-cell repair capacity. Other DNA-containing viruses such as SV40 and adenoviruses, which also replicate in the cell nucleus, show the small-plaque effect. Ionizing irradiation of herpes simplex virus type 1 (HSV-1) showed but little reduction in plaque-size.
MeSH terms
Adenoviruses, Human; Animals; Cell Line; Cytopathogenic Effect, Viral; Dose-Response Relationship, Radiation; Electrons; Herpesviridae; Humans; Radiation, Ionizing; Simian virus 40; Ultraviolet Rays; Virus Replication
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