[Transfer of genetic information from T to B human lymphocytes during an immune response to herpes simplex virus].
C R Seances Acad Sci D, 1979/7/09;289(2):217-20.
Anker P, Jachertz D, Stroun M, Brögger R, Lederrey C, Maurice PA
PMID: 229986
Abstract
Human blood lymphocytes carrying different allotypes were divided into B and T subpopulations and cultured in presence or in absence of ultraviolet inactivated Herpes Simplex Virus. Isolated B or T cells did not produce any antiherpetic activity. The B lymphocytes cultured in presence of 1 or 50% of the supernatant collected from virus exposed T cells synthesized on antiherpetic antibody with some allotypic markers of the T cell donor.
MeSH terms
Antibodies, Viral; B-Lymphocytes; Humans; Immunoglobulin Allotypes; In Vitro Techniques; Lymphocyte Cooperation; Simplexvirus; T-Lymphocytes
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