[Homogeneity of the erythrocyte volume distribution during chronic alcoholism macrocytosis (author's transl)].
Sem Hop, 1979/9/18-1979/9/25;55(31-32):1418-21.
Diakhaté L, Feo C, Buffet C, Tchernia G, Labayle D, Etienne JP
PMID: 228422
Abstract
The increase in volume of human erythrocytes during chronic alcoholic intoxication and its decrease after alcoholic deprivation was studied with a multichannel analyzer. When fractions of the population of red cells were separated by differential centrifugation the macrocytosis was found to be uniformly distributed. The presence of macrocytes was not related to changes of plasma osmolality or hyperhydration of red cells. A central origin was evoked, however, the role of the folic acid deficiency could not explain the macrocytosis, the mechanism of which remains to be elucidated.
MeSH terms
Adult; Aged; Alcoholism; Erythroblasts; Erythrocyte Volume; Erythrocytes, Abnormal; Female; Humans; Male; Middle Aged; Osmolar Concentration
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