Production of vesicular stomatitis virus with low infectivity by interferon-treated cells.
J Gen Virol, 1979/7;44(1):261-4.
PMID: 227998
Impact factor: 5.141
Abstract
In cultures of Ly cells treated with 10 or 30 reference units/ml of mouse interferon there was a 30 to 200 times reduction in the production of infectious vesicular stomatitis virus (VSV); virus particle production, as measured by VSV particle associated virus RNA, virus protein, and virus transcriptase, was inhibited by, at most, six times. These results suggested that interferon-treated cells produce VSV particles with low infectivity and resemble the findings in interferon-treated cells infected with murine leukaemia viruses.
MeSH terms
Animals; Cell Line; DNA-Directed RNA Polymerases; Interferons; Mice; RNA, Viral; Vesicular stomatitis Indiana virus; Viral Proteins; Virulence; Virus Replication
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