Occurrence of infection with group B coxsackievirus in rheumatic and nonrheumatic Filipino children.
J Infect Dis, 1979/9;140(3):415-8.
Limson BM, Chan VF, Guzman SV, Maaba MR, Mendoza MT
PMID: 227971
Impact factor: 7.759
Abstract
The pathogenesis of rheumatic fever has been linked to various immune mechanisms involving streptococcal antibodies and heart tissue antigens. Latent myocarditis due to group B coxsackievirus has also been considered as a possible conditioning factor. The validity of the role of infection with group B coxsackievirus in rheumatic fever was tested by determining the incidence of type-specific neutralizing antibodies in sera of Filipino children. Analysis of the results by means of a normal Z-test showed that the incidence in rheumatic children was not statistically significant in comparison to the incidence in asymptomatic children.
MeSH terms
Adolescent; Antibodies, Viral; Child; Coxsackievirus Infections; Enterovirus B, Human; Humans; Neutralization Tests; Philippines; Rheumatic Fever
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