TSH-receptor antibodies, HLA B8 and thyroid autoantibodies in patients with Graves' disease in therapeutically induced euthyroidism.
Experientia, 1979/10/15;35(10):1408-9.
Schernthaner G, Ludwig H, Schleusener H, Finke R, Kotulla P, Mayr WR
PMID: 227717
Abstract
The prevalence of TSH-receptor antibodies and of thyroid autoantibodies was studied in 48 HLA-typed patients with Graves' disease, who were in an euthyroid state after antithyroid therapy with methimazole. TSH-receptor antibodies, which were found in 35% of the patients, did not correlate with the positivity of HLA B8. By contrast the persistence of thyroid microsomal antibodies was significantly associated with HLA B8.
MeSH terms
Antibodies; Graves Disease; HLA Antigens; Humans; Isoantibodies; Methimazole; Microsomes; Receptors, Cell Surface; Thyroid Gland; Thyrotropin
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