Dopamine-sensitive adenylate cyclase activity in the caudate nucleus and adrenal medulla in Parkinson's disease and in liver cirrhosis.
J Neural Transm Suppl, 1978;(14):153-61.
Riederer P, Rausch WD, Birkmayer W, Jellinger K, Danielczyk W
PMID: 226659
Abstract
In human caudate nucleus and adrenal medulla dopamine-stimulated adenylate cyclase was measured. At a concentration of 100 microM dopamine, liver cirrhosis, carcinoma and therapy resistent parkinsonian patients showed decreased stimulation or even a reduction compared to controls. Therapy responding parkinsonian patients showed a decreased stimulation compared to controls, but this stimulation was significantly higher than in drug resistent patients.
MeSH terms
Adenylyl Cyclases; Adrenal Medulla; Aged; Carcinoma; Caudate Nucleus; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Female; Humans; Liver Cirrhosis; Male; Parkinson Disease
More resources
EndNote: Download