Plasma cyclic-AMP response to parathyroid hormone in Turner's syndrome and Albright's hereditary osteodystrophy.
Clin Endocrinol (Oxf), 1979/6;10(6):553-6.
Ashby JP, Renton WB, MacPherson JN, Price WH, Abbott SR
PMID: 225067
Impact factor: 3.523
Abstract
Purified bovine parathyroid hormone (BPTH) given by injection to five patients with Turner's syndrome, and seven healthy volunteers produced a significant rise in plasma cyclic AMP reacing a maximum within 10 min. In a pseudohypoparathyroid patient there was no increase. Urinary excretion of cyclic AMP exceeded the normal in three out of four patients with Turner's syndrome. Thus, if there is a relationship between Turner's syndrome and Albright's osteodystrophy it is with the incomplete form known as pseudo-pseudohypoparathyroidism.
MeSH terms
Adult; Cyclic AMP; Female; Humans; Middle Aged; Parathyroid Hormone; Pseudohypoparathyroidism; Turner Syndrome
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