Lithium antagonism of ethanol-induced depletion of cerebellar guanosine-3',5'-cyclic monophosphate and stimulation of striatal dopamine release.
J Stud Alcohol, 1979/5;40(5):401-7.
PMID: 224268
Abstract
Long-term lithium treatment antagonized the behavioral intoxication, depletion of cerebellar guanosine-3,5'-cyclic monophosphate and stimulation of striatal dopamine release induced by a single dose of ethanol. Blood ethanol concentrations were significantly reduced after lithium treatment in a dose-dependent manner.
MeSH terms
Alcohol Drinking; Animals; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Ethanol; Lithium; Male; Rats
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