The effect of sulfhydryl and amino group reagents on human lymphocyte--sheep erythrocyte rosettes.

Exp Cell Biol, 1979;47(3):183-9.

Tsokos GC, Papamichail MG

PMID: 223893

Abstract
We have studied the influence of certain chemical groups, located on the surface of lymphocytes or sheep red blood cells, on the ability of these cells to form spontaneous rosettes. We found that fluorescamine, which reacts with amino groups, inhibits rosette formation, while p-chloromercuriphenylsulfonic acid, which binds to sulfydryl groups, increases the percentage of the rosette-forming lymphocytes. The possible mechanism of action of the above reagents is discussed.
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