Effects of external calcium ions and strontium ions on interactions of isoprenaline and its competitive inhibitor with beta-adrenoceptors in the intestinal smooth muscle.

Eur J Pharmacol, 1979/5/15;55(4):397-9.

Takayanagi I, Takagi K

PMID: 223854

Impact factor: 5.195

Abstract
The effects were tested of Ca ions and Sr ions on interactions of isoprenaline and its competitive inhibitor with beta-adrenoceptors in the taenia caecum from the guinea pig. Ca ions were involved in the combination of isoprenaline with the beta-adrenoceptors but not involved in the combination of the competitive inhibitor with the beta-adrenoceptors. Sr ions could not substitute for Ca ions in the isoprenaline--receptor interaction.
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