Density-dependent growth inhibiting interactions between 3T3 and SV40-3T3 cells in mixed cultures.
Z Naturforsch C Biosci, 1979/3-1979/4;34(3-4):272-8.
PMID: 222083
Abstract
3T3 cells are shown to reduce SV40-3T3 cell population growth in a denisty-dependent manner in co-cultures of 3T3 and SV40-3T3 cells. The development of this inhibitory activity roughly parallels the development of density-dependent inhibition of growth in homogeneous 3T3 control cultures. The extent of reduction of SV40-3T3 growth can be manipulated by pretreatment of 3T3 cells with a high serum concentration. SV40-3T3 growth rates are reduced by factors between 10 and 20 under optimum inhibitory conditions as compared to SV40-3T3 growth in control cultures.
MeSH terms
Animals; Cell Division; Cell Line; Cell Transformation, Viral; Culture Media; Kinetics; Mice; Simian virus 40
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