Photosensitive epilepsy in Papio papio as a model for drug studies.
Electroencephalogr Clin Neurophysiol Suppl, 1978;(34):317-22.
PMID: 220003
Abstract
Photically-induced epilepsy in Papio papio provides a convenient model for assessing the efficacy and the acute neurological toxicity of new anticonvulsant drugs prior to clinical trial. Its drug sensitivity is broadly comparable to that of generalized seizures in man. It also shares some specific properties with syndromes of reflex epilepsy in man.
MeSH terms
Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Evaluation, Preclinical; Haplorhini; Papio; Phenytoin; Photic Stimulation; Seizures; Serotonin; Synaptic Transmission; gamma-Aminobutyric Acid
More resources
EndNote: Download